ASPE Reports
Displaying 81 - 100 of 4487 results. 20 results shown per page. Page 5 of 225.
Research Brief
Estimating Emergency Department Utilization of Select Drugs during Extreme Heat Events
We modeled the excess utilization of three commonly used drugs that treat heat-related illness in emergency departments during extreme heat events, using literature-derived estimates of emergency department visit rates for heat-related illness on extreme heat days and drug utilization rates from medical claims data.We estimate that extreme heat is associated with an average of 34,251 excess…
Report
Defining and Measuring the Resilience, Criticality, and Vulnerability of Medical Product Supply Chains
Recent disruptions in medical product supply chains have highlighted the need for stronger, more coordinated approaches to ensuring reliable access to medical products. Federal and private-sector leaders increasingly recognize the importance of building resilience, but there is great variability in how the concepts of medical supply chain resilience, criticality, and vulnerability are defined and…
Report
Longitudinal Analysis of Medical and Long-Term Services and Supports Use in the National Health and Aging Trends Study
This study examines the use of medical services and long-term services and supports by the population over age 65 over time.
ASPE Issue Brief
Use of Medicaid Personal Care Services in 2019 and 2020
This issue brief looks at changes in the utilization of personal care services among Medicaid beneficiaries from 2019 to 2020.
ASPE Issue Brief
Measuring Innovation of Medical Products
Increasing innovation in medical products is a policy priority. A first step to understanding changes in the level of innovation is to determine how to measure the baseline of innovation. Existing research employs a variety of measurement methods–scientific, therapeutic, and economic measures–to study trends in medical product (e.g., drugs, biologics, devices) innovation. Scientific innovation…
Report
Understanding the Role of Patient Advocacy Organizations in Funding Medical Product Research and Development
Patient advocacy organizations (PAOs) play a key role in medical product development. Many PAOs raise money to fund medical product development activities – such as basic science research, preclinical research, and clinical trials - for their condition of focus, whereas others fund or develop resources such as biobanks or patient registries to support the research community. PAOs fund medical…
Report
U.S. Biosimilar Market Entry Challenges and Facilitating Factors
There is ongoing interest in understanding ways to reduce drug prices and improve patient access to prescription drugs in the U.S. The estimated savings to the U.S. healthcare system from the use of biosimilars are significant. However, there is limited research on the cost of biosimilar development, expected market uptake for biosimilar entrants, barriers that may affect market entry decisions,…
Report
2026 HHS Evaluation Plan
The Fiscal Year (FY) HHS 2026 Evaluation plan includes four (4) evaluations reflecting evidence-building activities in different Operating and Staff Divisions across the U.S. Department of Health and Human Services (HHS). The selected evaluations highlight activities that will generate actionable evidence in FY 2026 on priority topics. They illustrate the kinds of evaluation activities planned…
ASPE Data Point
U.S. Population Prevalence of Prescription Psychiatric Medication Use Among Children and Adolescents, 2006-2023
Recent federal policy discussions have renewed focus on psychiatric medication use among children and adolescents. Psychiatric medications represent one evidence-based component within a spectrum of effective treatments for pediatric mental illness, alongside psychotherapy, family-based interventions, and school supports. Prior research has documented varying trends in psychotropic medication…
ASPE Issue Brief
Use of Participant Compensation in U.S. Clinical Research Studies
Providing compensation to clinical research participants to offset the costs associated with participation is often suggested as a way to improve recruitment and retention. However, relatively little is known about the landscape of compensation in clinical research. This study implemented a text mining approach to identify compensation across 7,648 U.S.-based clinical research studies, using…
Report
Engaging Patients to Enhance Data for Health Outcomes Research
To help patients make informed choices about their care, the United States Department of Health and Human Services (HHS) is improving the quality and accessibility of data needed to determine which treatments and care options work best. Resources from the Office of the Secretary Patient-Centered Outcomes Research Trust Fund (OS-PCORTF) support HHS data infrastructure projects that engage patients…
ASPE Issue Brief
Competition in the U.S. Therapeutic Biologics Market
Spending on biologics—large, complex molecules made from a living source—has been increasing over time and now represents nearly half of all U.S. prescription drug spending. Biosimilar competition for biologics is limited. Only 19% of biologics without patent protection have a marketed biosimilar—a highly similar version of the original biologic that is manufactured by a different entity than the…
ASPE Issue Brief
Empowering Patients to Participate in Clinical Trials
Increasing patient engagement in clinical trials offers opportunities to improve enrollment and retention in clinical trials, helping ensure interventions can be evaluated effectively and that clinical research dollars are used efficiently. Patient and provider awareness, trial exclusion criteria, proximity to trial sites, out-of-pocket medical expenses, and other factors all present as barriers…
ASPE Issue BriefPolicy Brief
Linking Health and Human Services Data Can Empower Patient Decisions and Increase Efficiency
This brief describes how enhancing linked data infrastructure across health and human services programs can improve efficiency, increase transparency through strengthening outcomes research, and empower patients and families to make more informed choices.
ASPE Issue BriefFact Sheet
Health Care and Child Care Costs Contribute to the Unsustainable and Growing Cost of Raising a Family in America
The cost of raising a family in America is high and continues to rise, with inflation rising by 23 percent between 2020 and 2025. For working families, some of the largest nondiscretionary expenses continue to be health care and child care. But even as spending rises, families are not getting healthier and, because of high costs, many are not able to choose the child care that best meets their…
ASPE Issue Brief
Understanding the Impact and Costs Associated with Medical Device Shortages During the COVID-19 Pandemic on Providers, Health Systems, Patients, and Manufacturers
We conducted a landscape analysis to understand the characteristics, impacts, and costs associated with medical device shortages during the COVID-19 pandemic in the U.S. Among health systems, nursing homes and rural hospitals were the most impacted by medical device shortages due to high demand and supply transportation issues.
ASPE Issue BriefReport
Rebalancing of Medicaid-Funded Long-Term Services and Supports, 2016-2019
Shifting spending and delivery of long-term services and supports (LTSS) from institutions to the home and community is often referred to as rebalancing. This report and brief describe variation in LTSS rebalancing between 2016 and 2019 by enrollee age, health condition, and demographic factors. During the study period, nationally, older adults without an intellectual or developmental disability…
ASPE Issue Brief
Long COVID among Essential Workers, Non-Essential Workers, and Not Working Persons in the United States, 2022-2023
The Office of the Assistant Secretary for Planning and Evaluation (ASPE) released a report examining trends in prevalence of Long COVID among different types of workers and among individuals who were not working. Workers in different occupations face different risks of COVID infection, and, potentially, Long COVID, depending on the nature of their work.
Report
Behavioral Health Prevalence, Utilization, and Spending Among Older Adult Medicare Beneficiaries: A Chartbook
Older adults with behavioral health disorders often experience worse health and functional outcomes, have higher rates of emergency department visits, use more medications, and have higher health care costs than those without a behavioral health disorder. There is need for a greater understanding of the extent to which older adults experience behavioral health disorders. Updated evidence is also…
ASPE Issue Brief
Trends in Medicaid and CHIP Telehealth Part III: Telehealth Utilization Trends Among Child Enrollees, 2019-2021
This report examines national trends in telehealth service delivery to enrollees ages 0-18 years from 2019 to 2021, by enrollee characteristics such as age group and race and ethnicity. Services delivered via telehealth to pediatric Medicaid and CHIP enrollees rapidly expanded with the onset of the COVID-19 Public Health Emergency (PHE) in 2020 and remained higher than pre-PHE levels in 2021.…