KEY POINTSCDC reported a provisional 2025 age-adjusted death rate of 689.2 deaths per 100,000 population, the lowest ever reported death rate and 4.6% below the final 2024 rate of 722.1 deaths per 100,000 population.CDC notes that the published 2024
Data Sources & Measurement
Reports
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The U.S. Age-Adjusted Death Rate Reached a Record Low in 2025: What Drove the Decline?
Report
Evidence-Based Measures for Chronic Disease Outcomes: A Review of Available Measures for Emergent HIV Therapies
Executive SummaryBackground. The U.S. Department of Health and Human Services Office of the Assistant Secretary for Planning and Evaluation (ASPE) supports intradepartmental efforts to build data capacity for patient-centered outcomes research and to improve evidence generation for healthcare decision-making.
Report
Evidence-Based Measures for Chronic Disease Outcomes: A Review of Available Measures for Emergent Sickle Cell Disease Therapies
Executive SummaryBackground. The United States (U.S.) Department of Health and Human Services Office of the Assistant Secretary for Planning and Evaluation (ASPE) supports intradepartmental efforts to build data capacity for patient-centered outcomes research and to improve evidence generation for healthcare decisionmaking.
Report
Harnessing the Value of Electronic Health Record Data for Research
The United States (U.S.) faces urgent health challenges, including poor maternal and childhood health outcomes, childhood obesity, opioid use disorder, cancer, and chronic conditions, which require personalized care tailored to each patient’s unique circumstances.
Report
Assessing the Feasibility of Creating a National Behavioral Health Workforce Database
The U.S. behavioral health (BH) workforce faces significant shortages and distribution disparities, hindering access to quality care and worsening health outcomes. A comprehensive, centralized database of BH providers is vital for advancing patient-centered outcomes research (PCOR), comparative effectiveness research (CER), and evidence-based policymaking.
Environmental Scan, Research Brief
Availability and Access of Bacterial Infection Diagnostics in the United States
Key Findings:
ASPE Issue Brief
Child Support Engagement in Rural and Non-Rural Counties: More Engagement and Lower Amount Owed in Rural Areas
This brief describes differences in engagement in child support for custodial parents living in rural and nonrural areas. Key findings are below.Key Points:
Report
Claims and Provider Payment Data Gaps for Responding to COVID-19
This report and accompanying discussion by ASPE and NORC highlights the claims data limitations identified during the COVID-19 Public Health Emergency Health (PHE) and provides considerations to address these limitations. The report identifies that limitations related to claims data were existing issues, exacerbated by, but not unique to, the COVID-19 PHE.
Report
Linking State Medicaid Data and Birth Certificates For Maternal Health Research
This report presents the set of guiding principles for linking state Medicaid data with birth certificates that was developed by state and national experts and leaders. These guiding principles can be implemented to create a multistate linked database that researchers would be able to access and use for research on maternal health, including patient-centered outcomes research (PCOR).
Report
Landscape of Area-Level Deprivation Measures and Other Approaches to Account for Social Risk and Social Determinants of Health in Health Care Payments
Improving health equity in the United States is a priority for the Biden-Harris Administration in order to address longstanding disparities in health outcomes. Health inequities can be conceptualized and measured as drivers of differences in health outcomes.