Advisory Council October 2014 Meeting Presentation: Research Progress

Monday, October 27, 2014

NAPA Research Progress Report

Richard J. Hodes, M.D.
Director
National Institute on Aging

New Alzheimer’s-related Initiatives

• Biomarkers of Alzheimer’s Disease in Down Syndrome (R01)
  • NIA & NICHD  
• Interdisciplinary Research to Understand the Vascular Contributions to Alzheimer's Disease (R01)
  • NIA & NINDS
• Immune and Inflammatory Mechanisms in Alzheimer's Disease (R01)
  • NIA

2015 Summit Update

• February 9th-10th, 2015
• National and international participation anticipated
• Summit registration now open
• G7 wrap-up on March 3-4, 2015, in Geneva, planned by the WHO

Progress on AD-Related Dementias

• Research recommendations from ADRD 2013 were published in Neurology on August 26, 2014.
• New Studies of FTD
  • FTD clinical research consortium to support the development of FTD therapies (NINDS & NCATS/ORDR)
  • Longitudinal natural history study of familial FTD (NIA & NINDS)
  • A large program project to understand the cellular disease processes that lead to ALS and FTD (NINDS)
• Small Blood Vessels: Big Health Problems? Workshop
  • Held September 18-19, 2014
  • Integrated research findings across organ systems, including the brain
  • Identified research gaps, which will be published in a white paper
  • Sponsored by NINDS, NHLBI, NEI, Office of Disease Prevention, Office of Research on Women’s Health

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NOTE: http://iadrp.nia.nih.gov/.

IADRP – Current Members

US Organizations	International Organizations
US Federal Government (6 agencies) Alzheimer’s Association Alzheimer’s Drug Discovery Foundation Ellison Medical Foundation Cure Alzheimer’s Fund Geoffrey Beene Foundation Patient-Centered Outcomes Research Institute   State of Texas State of California State of Wisconsin State of Oregon State of Virginia	Government of Poland Government of Australia Alzheimer’s Society of Canada Alzheimer’s Research UK Alzheimer’s Society of UK Alzheimer’s Australia Dementia Research Foundation   UK Medical Research Council Federazione Alzheimer Italia Sao Paulo Research Foundation (FAPESP)
	Currently coding and validating AD project data Brain Canada Canadian Institute s of Health Research

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