Understanding the High Prevalence of Low-Prevalence Chronic Disease Combinations: Databases and Methods for Research. Appendices


The appendices listed below are supplemental materials and are attached to the white paper.

Appendix A - Literature Search Methodology

The literature search methodology outlines the MEDLINE search terms that were used to conduct the literature review of the peer-reviewed and grey literature related to prevalence of MCC, disease combinations, diagnosis coding, and databases and analytic techniques that have been used to conduct chronic disease research. The number of papers that were identified with each search term and combination are presented.

Appendix B – Review of National Datasets and Data Systems: Summary Tables

The review of national datasets provides a descripton of seventeen national data systems that can be used for multiple chronic conditions research, including a description of each data system, the diagnosis information measured in each data system, the cost, utilization, and clinical information captured in each data system, and the strengths, limitations, and appropriateness of each data system for MCC research.

Appendix C – Clinical Classification Systems ( Grouper ) Review

The Clinical Classification Systems (Grouper) Review provides a summary of fourteen systems for organizing and aggregating diagnosis codes into different disease categories, and an assessment of each grouper system’s feasibility for disease complexity research.

Appendix D - Technical Advisory Group List

The Technical Advisory Group (TAG) List provides of experts consulted about the overall conduct of the studies and their affiliations. TAG members participated in an initial in-person meeting in December 2012 and provided feedback on the original literature review to determine additional databases, grouping systems, and methods for studying MCC in disparities populations. TAG members then participated in a second meeting by teleconference in May 2013 to review and provide feedback on the first draft of the White Paper.

Appendix E - Key Informants

The list of key informants includes the individually interviewed experts and their affiliations. Key informants were identified by the ASPE Project Officers and the Technical Advisory Group (TAG). Key informant interviews were conducted to provide the Project Team with in-depth expertise on topics covered in the White Paper. Findings from the Key Informant Interviews have been incorporated throughout the White Paper.

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