Performance Improvement 1999. National Institutes of Health



TITLE: Evaluation of the International Cooperative Biodiversity Groups (ICBG)

ABSTRACT: The International Cooperative Biodiversity Groups (ICBG) are the first large scale, multi-country attempt to combine natural products drug discovery with measures to promote conservation of diverse biological species around the world. This study evaluated the ICBGs to determine progress in achieving goals of stimulating new drug discovery while promoting biodiversity conservation and sustainable economic development. The findings from this study are to be used to assist ICBG sponsors in managing the program and to provide useful ideas on innovations and lessons learned from the individual programs. The results indicate that each ICBG group made real accomplishments toward finding new drug lead compounds, advancing conservation techniques, and promoting sustainable economic development through their multi-disciplinary research and capacity-building activities. All ICBGs discovered novel bio-active compounds and developed systems to inventory and archive information gained on the biological diversity of their respective source countries. Over 3,000 species had been collected during the first four years. The ICBGs also developed new approaches to sample collection and testing and improving methods. The ICBGs produced over 6,000 extracts from samples collected and submitted these for testing in at least 60 different assays in15 different therapeutic areas. Also significant was that all ICBGs provided training in biodiversity conservation, drug discovery and drug development in their source country. The results from this evaluation study will provide a useful model and significantly contribute to scientific capacity building in future biodiversity programs in other countries.

AGENCY SPONSOR: Fogerty International Center


PHONE NUMBER: 301-496-2571

PIC ID: 6641

PERFORMER ORGANIZATION: Battelle Corporation, Arlington, VA

TITLE: Evaluation of the NHLBI Programs of Excellence in Molecular Biology: Summary Report and Final Report

ABSTRACT: The National Heart, Lung, and Blood Institute, the second largest research institute at NIH, developed and implemented an initiative (Programs of Excellence in Molecular Biology--POEMB) to stimulate the use of molecular biology approaches in areas where these new techniques have been underutilized; and by providing opportunities for investigators who have the potential for establishing or redirecting research. The purpose of this evaluation was to measure the extent to which the initiative realized its objectives and its appropriateness as a model for promoting the application of new research techniques and methodologies to existing areas of research. In summary, the program resulted in an increase in individuals pursuing and applying the techniques of molecular biology and related fields of study which should result in greater application of these techniques in the future.

AGENCY SPONSOR: National Heart, Lung, and Blood Institute


PHONE NUMBER: 301-496-3620

PIC ID: 5584

PERFORMER ORGANIZATION: Battelle Human Affairs Research Centers, Seattle WA


TITLE: Evaluation of the National Heart, Lung and Blood Institute's Short-Term Training for Minority Students Program

ABSTRACT: In order to increase the number of under-represented minority individuals pursuing advanced degrees in the biomedical and behavioral sciences, the NHLBI established the Short-Term Training for Minority Students Program (STMSP). The program: (1) provides minority undergraduate and graduate students and students in health professional schools exposure to opportunities inherent in research careers in areas relevant to cardiovascular, pulmonary, and hematologic health and diseases, transfusion medicine, and sleep disorders; (2) attracts highly qualified minority students into biomedical and behavioral research careers in the areas of heart, lung and blood health, transfusion medicine, and sleep disorders; and (3) bolsters the already short supply of qualified minority investigators. The evaluation found that STMSPs are successful in their efforts to: attract highly qualified minority individuals; expose trainees to a broad range of quality research experiences; satisfy trainees with their level of mentor involvement; positively affect trainee education and career decisions.

AGENCY SPONSOR: National Heart, Lung, and Blood Institute


PHONE NUMBER: 301-402-3421

PIC ID: 6118.1