National Plan to Address Alzheimer's Disease: 2016 Update. Strategy 1.E: Facilitate Translation of Findings into Medical Practice and Public Health Programs

08/01/2016

Reporting Research Findings. NIA operates the ADEAR Center, the primary Federal Government resource for information about AD/ADRD, research, and caregiving. The ADEAR Center educates the public about the latest research findings and clinical trial participation via free, evidence-based information available online and in print. In addition, NIA disseminates research findings through the media, social media, and annual research progress reports.

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Resources for the Dementia Services Community. Since 2012, the NIA and ACL have co-hosted an annual webinar series on AD/ADRD to educate professionals and improve coordination of federal resources between the research and aging services communities. In 2014, CDC joined as a sponsor and Continuing Education credits were made available for participants. In 2014, a key focus of the series was how to forge successful community collaborations serving people with AD/ADRD, as well as updates on resources and research. Free continuing education is available through 2016 to professionals who need it when they view recorded webinars.

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Exploring the Evidence for Prevention. In 2015, the NIH initiated a project involving the Agency for Healthcare Research and Quality (AHRQ), and the National Academies of Sciences, Engineering, and Medicine's (NAS's) Health and Medicine Division (HMD), to conduct a systematic review of the evidence on prevention of clinical Alzheimer's-type dementia, MCI, and age-related cognitive decline (AHRQ), and to shape these findings into a set of recommendations for public health practice and research (HMD). This effort is driven by the intense interest in recent years -- in the United States and internationally -- to identify ways to reduce the risk for cognitive decline and AD/ADRD. This project will provide valuable information regarding scientific support for existing interventions. A report is expected in 2017.

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DoD Work on Alzheimer's Disease. Since 2011, the U.S. Department of Defense (DoD) Peer Reviewed Alzheimer's Research Program (PRARP) has been devoted to understanding the association between Traumatic Brain Injury (TBI) and AD/ADRD. Equally important, the program also focuses on reducing the burden on caregivers and individuals living with the common symptoms of TBI and AD/ADRD, especially in the military community. Funding for FY 2013 funding of $12 million was executed by September 30, 2014. For FY 2013, 37 pre-proposals were received for the Convergence Science Research Awards and Military Risk Factor Awards. A total of eight awards were made, bringing the number of funded projects to 29. Using the Common Alzheimer's Disease Research Ontology criteria, FY 2013 funding was distributed among the following categories:

  • Category A. Molecular Pathogenesis and Pathophysiology of Alzheimer's Disease (4 Projects).
  • Category B. Diagnosis, Assessment and Disease Monitoring (3 Projects).
  • Category D. Epidemiology (1 Projects).

     

In the period from October 1, 2014 to March 12, 2015, three Program Announcements were released to fund research in basic and translational sciences. FY 2015 funding was $12 million. The announcements asked scientists to address one of five overarching research challenges (Paucity of Research Resources; Paucity of Clinical Studies; Need for Diagnostic Technologies, Tests, Interventions, or Devices; Quality of Life; or Caregiver Burden). Awards were made by September 30, 2015.

During the April 31, 2014-March 1, 2015 annual reporting period, one patent was applied for and 14 publications were produced. The PRARP continues partnerships across the DoD, VA, and other governmental agencies by having their staff provide guidance to the PRARP as participants at the program's regular meetings.

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