National Plan to Address Alzheimer's Disease: 2016 Update. Strategy 1.A: Identify Research Priorities and Milestones

08/01/2016

2015 Alzheimer's Disease Research Summit Advances Research Agenda. In February 2015, the NIH Alzheimer's Disease Research Summit 2015: Path to Treatment and Prevention expanded on the research agenda set in place at the first of such summits held in 2012. The 2015 gathering brought hundreds of experts in Alzheimer's and other chronic diseases together to identify critical knowledge gaps and set priorities for the kinds of new resources, infrastructure, and multi-stakeholder partnerships needed to fully realize emerging research opportunities. In response to goals and objectives discussed at the 2015 summit, NIH issued ten Funding Opportunity Announcements (FOAs) in the fall of 2015 inviting new grant applications on topics covering a broad spectrum of AD research. These funding announcements offered an array of opportunities for investigators, covering studies of epidemiology, basic molecular and cellular mechanisms, diagnosis and prediction, health disparities, caregiving, clinical trials, and brain aging, among others. The research community responded robustly to these new opportunities, and the first set of awards will be made before October 2016.

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2016 Summit on Alzheimer's Disease-Related Dementias (ADRD) Research. NIH also hosted the Alzheimer's Disease-Related Dementias 2016 Summit in March 2016 to update the recommendations on national research priorities for FTD, LBD, multiple etiology dementia, vascular contributions to cognitive impairment and dementia (VCID), and health disparities in dementia that came out of the 2013 ADRD Summit. The meeting drew hundreds of experts across diverse fields of dementia research as well as advocates, patients, and caregivers. Their goals were to review progress and update recommendations based on scientific progress, to prioritize the important scientific questions that need to be answered to advance our understanding of these complex disorders, and to identify how federal and non-governmental organizations (NGOs) can further and most effectively collaborate to address these research priorities. Final recommendations from the meeting will be released, following approval by the National Advisory Neurological Disorders and Stroke Council and the NAPA Advisory Council later in 2016.

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