PMI was announced in 2005, with $1.2 billion in funding planned over a five-year period. A January 2007 article in the Seattle Times suggested that the Gates Foundations experience in reducing malaria through simple, inexpensive interventions may have prompted the US government to fund such an initiative.
PMI builds on a long record of involvement by the U.S. government in anti-malaria efforts. USAID and the CDC have been involved with anti-malaria research and programs since the 1950s. PMI consolidates and expands USAID malaria-related funding and activities under a single umbrella, and builds on USAIDs recent work addressing production capacity of malaria treatments and bed nets, as well as developing policies for effective treatment adoption. Since 2001 the U.S. has also contributed to the Global Fund to Fight AIDS, Tuberculosis, and Malaria, along with making contributions to and participating in other international and multilateral organizations that help lead and coordinate the fight against malaria.