This study relied on several types of sources for information about cocaine pharmacotherapies and the market barriers to their development. These included:
- Analysis of the current market for cocaine abuse pharmacotherapies;
- Quantitative modeling of multiple hypothetical scenarios of pharmacotherapy development;
- Case studies of four selected pharmacotherapies; and
- Detailed interviews with executives of several private firms (e.g., pharmaceutical companies, venture capital firms) with real or potential interest in substance abuse and/or other central nervous system drug development.
The numbers of case studies and industry interviews were expressly limited by the scope of this project. Therefore, the information gathered from these sources cannot be considered to be systematically representative of pharmacotherapy experience or industry opinions pertaining to the market for substance abuse pharmacotherapies.