The government was involved in aspects of development and marketing for each of the four case study drugs. These phases, adapted from the 1995 IOM report, include discovery, clinical studies, NDA phase, and marketing.
|Case Study Drugs|
|Funding of basic science research|
|Funding of clinical trials|
|Orphan drug status|
|Other market exclusivity|
|Less stringent phase IV clinical trial requirements|
|Source: The Lewin Group|