HHS Strategic Plan, Fiscal Years 2007–2012 (Strategic Plan). Alzheimer’s Disease

11/22/2015

Alzheimer’s disease, the most common cause of dementia among people older than 65, is one of the most serious threats to the Nation’s health and economic well-being. Currently, 4.5 million Americans are affected by the disease; that number is expected to almost triple by 2050. Those suffering from Alzheimer’s disease advance inexorably, from early, mild forgetfulness to a severe loss of mental function and inability for self-care. Existing research suggests that Alzheimer’s disease pathology begins to develop in the brain long before clinical symptoms yield a diagnosis. The ability to make an accurate early diagnosis of Alzheimer’s disease would allow targeted intervention before cognitive loss becomes significant. NIH is searching for valid, easily attainable biological markers that could help identify biological markers for early disease. For example, NIH will support research to examine one promising approach that involves using coated gold nanoparticles as bioprobes to measure the concentrations of substances that correlate with Alzheimer’s disease. NIH will also continue to support the Alzheimer’s Disease Neuroimaging Initiative. The 5-year, 50-site project represents the most comprehensive effort to date to develop neuroimaging and other biomarkers for the changes associated with mild cognitive impairments and Alzheimer’s disease. The ongoing Genetics Initiative will also support the development of resources necessary for identifying late-onset risk factor genes, associated environmental factors such as physical activity and diet, and their interactions.

View full report

Preview
Download

"hhsplan2007.pdf" (pdf, 21.68Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplantoc.pdf" (pdf, 139.08Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplan2007es.pdf" (pdf, 1.94Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc1.pdf" (pdf, 3.12Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc2.pdf" (pdf, 3.29Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc3.pdf" (pdf, 3.53Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc4.pdf" (pdf, 3.05Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc5.pdf" (pdf, 3.92Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanc6.pdf" (pdf, 1.04Mb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappA.pdf" (pdf, 247.94Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappB.pdf" (pdf, 207.69Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappC.pdf" (pdf, 218.21Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappD.pdf" (pdf, 202.15Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappE.pdf" (pdf, 242.27Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappF.pdf" (pdf, 199.16Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappG.pdf" (pdf, 189.41Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®

View full report

Preview
Download

"hhsplanappH.pdf" (pdf, 401.54Kb)

Note: Documents in PDF format require the Adobe Acrobat Reader®. If you experience problems with PDF documents, please download the latest version of the Reader®