From time to time, HHS agencies disseminate influential scientific, financial and statistical information as defined in the OMB Guidelines. In such instances, care is taken to ensure that the information is substantially reproducible and replicable. This goal is accomplished by using reliable data sources and sound analytical techniques, and by employing a high degree of transparency about the data, sources, methods, measures, assumptions and limitations used to develop the information in order to facilitate reproducibility by qualified third parties. In the case of original or supporting data, most major epidemiological and statistical activities sponsored by HHS agencies have well developed public use data dissemination programs that make much of the data available to the public in standardized, de-identified micro-data files.
Because of confidentiality, ethical and feasibility constraints and legal obligations to third parties supplying the information, there may be instances where original or supporting data may not be available to the public, but HHS agencies typically will work with qualified third parties to facilitate understanding, and transparency in data sources and methods will be emphasized in the report or in reference documents. In the case of analytical studies, HHS agencies will make provisions for sufficient transparency about data and methods so that an independent reanalysis could be undertaken by a qualified member of the public.