Analytical Framework for Examining the Value of Antibacterial Products. A.2.2 Current Treatment


While uncomplicated SSTIs may be treated in the outpatient setting with oral dicloxacillin–flucloxacillin  or cephalexin (or, alternatively, penicillin, amoxicillin/clavulanic acid, macrolides, tetracyclines, or clindamycin), more serious SSTIs often require parenteral administration of antimicrobial agents, such as ceftriaxone, clindamycin, penicillins, and cefazolin In cases of complicated SSTIs caused by MRSA, intravenous administration of vancomycin, linezolid, daptomycin, telavancin, or clindamycin is recommended. Outpatient treatment of MRSA infections may involve oral clindamycin, trimethoprim-sulfamethoxazole, doxycycline, minocycline, linezolid, or cephalexin.

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