Analytical Framework for Examining the Value of Antibacterial Products. A.1.1 Background


Acute bacterial otitis media (ABOM) is an infection of the middle ear.. It is the most common infection for which antibacterial drugs are prescribed for children in the United States, though it can also occur in adults. Streptococcus pneumoniae is the most commonly identified bacterium in ABOM among children, found in approximately 25% to 50% of cases; Haemophilus influenzae is found in 15%-30% of cases, and Moraxella catarrhalis in 3% to 20% of cases

The economic burden associated with acute otitis media (including non-bacterial causes) is substantial, particularly when the indirect costs associated with lost time from school and work (for parents) are taken into account. According to a 2001 study, the direct cost of acute otitis media in was estimated to be $1.96 billion in 1995, and the indirect cost was estimated at $1.02 billion Recent studies of outpatient survey data indicate that there are roughly between 9 million and 16 million physician office visits for acute otitis media every year

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