Analytical Framework for Examining the Value of Antibacterial Products. 4.1 Background


From a public health standpoint, development of vaccines that effectively prevent illness caused by infectious agents is an attractive alternative or complement to developing drugs that treat those diseases, as it may reduce the need for consumption of antibacterial drugs and thus slow the development of antibacterial drug resistance. Vaccines for highly contagious diseases such as smallpox, polio, and measles have been used for many years, essentially eradicating those diseases in the United States and many other parts of the world. Vaccines developed more recently include a pneumococcal conjugate vaccine for children as well as a meningococcal vaccine.  This section summarizes the key demand- and supply-side challenges associated with the development of new vaccines.

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