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Advisory Council October 2014 Meeting Presentation: Research Progress

ADVISORY COUNCIL ON ALZHEIMER'S RESEARCH, CARE, AND SERVICES

Monday, October 27, 2014

 

NAPA Research Progress Report

Richard J. Hodes, M.D.
Director
National Institute on Aging

New Alzheimer’s-related Initiatives

2015 Summit Update

  • February 9th-10th, 2015
  • National and international participation anticipated
  • Summit registration now open
  • G7 wrap-up on March 3-4, 2015, in Geneva, planned by the WHO

Progress on AD-Related Dementias

  • Research recommendations from ADRD 2013 were published in Neurology on August 26, 2014.
  • New Studies of FTD
    • FTD clinical research consortium to support the development of FTD therapies (NINDS & NCATS/ORDR)
    • Longitudinal natural history study of familial FTD (NIA & NINDS)
    • A large program project to understand the cellular disease processes that lead to ALS and FTD (NINDS)
  • Small Blood Vessels: Big Health Problems? Workshop
    • Held September 18-19, 2014
    • Integrated research findings across organ systems, including the brain
    • Identified research gaps, which will be published in a white paper
    • Sponsored by NINDS, NHLBI, NEI, Office of Disease Prevention, Office of Research on Women’s Health

Web Screen Shot #1

Screen Shot: International Alzheimer's Disease Research Portfolio Home Page. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/.

IADRP – Current Members

US Organizations International Organizations
  • US Federal Government (6 agencies)
  • Alzheimer’s Association
  • Alzheimer’s Drug Discovery Foundation
  • Ellison Medical Foundation
  • Cure Alzheimer’s Fund
  • Geoffrey Beene Foundation
  • Patient-Centered Outcomes Research Institute  
  • State of Texas
  • State of California
  • State of Wisconsin
  • State of Oregon
  • State of Virginia
  • Government of Poland
  • Government of Australia
  • Alzheimer’s Society of Canada
  • Alzheimer’s Research UK
  • Alzheimer’s Society of UK
  • Alzheimer’s Australia Dementia Research Foundation  
  • UK Medical Research Council
  • Federazione Alzheimer Italia
  • Sao Paulo Research Foundation (FAPESP)
Currently coding and validating AD project data
  • Brain Canada
  • Canadian Institute s of Health Research

Web Screen Shot #2

Screen Shot: International Alzheimer's Disease Research Portfolio Home Page. Reports and Publications circled. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/.

Web Screen Shot #3

Screen Shot: IADRP Reports and Publications Page. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/content/reports-and-publications.

Web Screen Shot #4

Screen Shot: IADRP Reports and Publications Page. Drug Development: Repurposing and Combinations circled. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/content/reports-and-publications.

Web Screen Shot #5

Screen Shot: IADRP Drug Development: Repurposing and Combinations page. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/content/drug-development-repurposing-and-combinations-test.

Web Screen Shot #6

Screen Shot: IADRP Drug Development: Repurposing and Combinations page. RFA-AG-13-013: Interdisciplinary Approach to Identification and Validation of Novel Therapeutic Targets for Alzheimer's Disease (R01) circled. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/content/drug-development-repurposing-and-combinations-test.

Web Screen Shot #7

Screen Shot: IADRP RFA-AG-13-013 Page. See NOTE for URL.
NOTE: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-013.html.

Web Screen Shot #8

Screen Shot: IADRP Drug Development: Repurposing and Combinations page. Category C: Translational Research and Clinical Interventions - 1 Drug Discovery circled. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/content/drug-development-repurposing-and-combinations-test.

Web Screen Shot #9

Screen Shot: IADRP Translational Research and Clinical Interventions Page. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/quick-search?f[0]=field_cadro%3A174966&f[1]=field_cadro%3A174971.

Web Screen Shot #10

Screen Shot: IADRP Translational Research and Clinical Interventions Page. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/quick-search?f[0]=field_cadro%3A174966&f[1]=field_cadro%3A174971.

Web Screen Shot #11

Screen Shot: IADRP Translational Research and Clinical Interventions Page. A Needle in a Haystack: New Approaches to Alzheimer's Drug Discovery From Natural circled. See NOTE for URL.
NOTE: http://iadrp.nia.nih.gov/quick-search?f[0]=field_cadro%3A174966&f[1]=field_cadro%3A174971.

Web Screen Shot #12

Screen Shot: NIH Research Portfolio Online Reporting Tools, A Needle in a Haystack: New Approaches to Alzheimer's Drug Discovery From Natural. See NOTE for URL.
NOTE: http://projectreporter.nih.gov/project_info_description.cfm?aid=7783786&icde=6873524.

Web Screen Shot #13

Screen Shot: NIH Research Portfolio Online Reporting Tools, A Needle in a Haystack: New Approaches to Alzheimer's Drug Discovery From Natural. Results circled. See NOTE for URL.
NOTE: http://projectreporter.nih.gov/project_info_description.cfm?aid=7783786&icde=6873524.

Web Screen Shot #14

Screen Shot: NIH Research Portfolio Online Reporting Tools, A Needle in a Haystack: New Approaches to Alzheimer's Drug Discovery From Natural Results. See NOTE for URL.
NOTE: http://projectreporter.nih.gov/project_info_results.cfm?aid=7783786&icde=6873524.

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