Skip to main content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Advisory Council August 2016 Meeting Presentation: Indiana University Dissemination of the Aging Brain Care Program

Monday, August 1, 2016

Indiana University Dissemination of the Aging Brain Care Program

Malaz Boustani, MD, MPH
Founding Director, Chief Innovation & Implementation Officer,
Sandra Eskenazi Center For Brain Care Innovation
Indiana University Center for Health Innovation and Implementation Science

IU Team

  • Mentors & peers
    • Chris Callahan
    • Greg Sachs
    • Mary Austrom
    • Siu Hui
    • Daniel Clark
    • Su Gao
    • Lisa Harris
    • Patrick Monahan
    • Wanzhu Tu
    • Anthony Perkins
  • Mentees:
    • Noll Campbell
    • Babar Khan
    • Nicole Fowler
    • Michael LaMantia
    • Richard Holden
    • Daniel Bateman
    • Sophia Wong
    • Ashley Overlay
    • Nadia Adams
    • Cathy Alder
    • Ben Zarzour

 

  • Potential Conflict of Interest in the past 12 months
    • Hold equity in a preferred population health management (PPHM), LLC. PPHM is the distributing network for the IU ABC program.
    • Member of the Beacon Advisory Board for Astra-Zneca.

 

  • Source of Funding:
    • For Brain Care Discovery:
      • K23AG026770; R01AG029884; R01AG040220; R01AG034205; P30AG024967; R01HS019818; and R01HS10884.
    • For Brain Care Delivery:
      • R24MH080827; 1C1CMS331000-01-00; 1L1CMS331444-01-00; and Eskenazi Health Foundation.

Objectives

  • Describe the structure, the tools, the staffing models, and effectiveness of the IU Aging Brain Care model.

Indiana University Reaction

  • Developed the Aging Brain Care Model (ABC beta ) (2000-2001).
  • Evaluated the model in RCT* (2001-2006).
  • Translated the model into a local clinical program (ABC 1.0) (2007).
  • Served 1,000 patients in Indianapolis (2012).
  • Developed a scalable version (ABC 2.0) (2012).
  • Served 5,000 patients in Indiana (2015).
  • Active distribution of the ABC 2.0 (2015)
  • Developing an advanced scalable version (ABC 3.0) (2016)

*RCT: Randomized Controlled Trial

The Aging Brain Care Model (ABC beta)

  • Primary Care Clinician (Hospitalists):
    • detect and treat delirium
    • detect and treat BPSD
    • Enhance cholinergic system by
      • Prescribe ChEIs
      • Discontinue Anticholinergic
  • Caregiver Focus:
    • Problem solving skills
    • Counseling
    • Respite care
    • Support group
  • Expert Team:
    • Geriatrician
    • Social Psychologist
    • GeroPsychiatrist
  • General Environmental Modification:
    • Medication adherence support
    • Home safety assessment

BPSD: Behavioral and psychological symptoms
ChEIs: Cholinesterase inhibitors

Callahan et al, JAMA 2006; Austrom et al, Gerontologist 2004; Boustani et al, JCIA 2006

Work Force for ABC Model from 1.0 to 3.0

Today ABC 2.0: : M-F 8-5 p.m. about $ 100 p.m.p.m., focusing on dementia / depression
Future ABC 3.0: 24/7 about $ 50 p.m.p.m., almost all brain conditions

  • ABC 1.0 -- MD; RN & SW
  • ABC 2.0 -- MD; RN & SW; CCA
  • ABC 3.0 -- MD; RN & SW; CCA; Patients and informal caregivers

p.m.p.m.=per member per month; MD=medical doctor; RN=registered nurse; SW=social worker; CCA=care coordinator assistant; eMR ABC=electronic medical record ageing brain care (a specialized software application for the model)

IT Support of ABC Model from 1.0 to 3.0

  • ABC 1.0 -- MD, eMR-ABC; RN / SW + eMR-ABC
  • ABC 2.0 -- MD, eMR-ABC; RN / SW + eMR-ABC; Care Coordinator Assistants + eMR-ABC
  • ABC 3.0 -- MD, eMR-ABC; RN / SW + eMR-ABC; Care Coordinator Assistants + eMR-ABC; Informal Caregiver + AVATAR

Standardized Minimum ABC 2.0 Care

  1. Check Hospital & ER Alerts every day
  2. Coordinate with Inpatient services
    • Alert hospital team of presence of cognitive or mood problems
    • Medications conciliation
    • Connect with family caregiver
    • Request Geriatric consult (If available)
    • Coordinate post discharge transition
  3. Post discharge care
    • Home visit within 72 hours of discharge
    • Medication reconciliation
    • Coordinate Home Care visit
    • Coordinate post hospital orders
    • Deliver Delirium protocol and handout
  4. Ongoing Aging Brain Care
    • Manage Depression
      • Problem Solving Therapy
      • Pharmacotherapy
      • Cognitive behavioral Therapy
    • Manage Cognitive Impairment
      • Cholinesterase inhibitors (if needed)
      • D/C medications with adverse cognitive effects (Anticholinergics, Histamine 2 antagonists, Benzodiazepines)
      • Caregiver problem solving coaching
      • Medication adherence support

Callahan et al, Aging & Mental Health 2011; Boustani et al, Aging & Mental Health 2011; LaMantia et al, JAGS 2015

The Current Tools of ABC 2.0

  • Mobile office
  • HABC Monitor for both self and Caregiver report
  • eMR-ABC population management software
  • Mobile HABC App for Informal Caregiver
  • ABC Replication Manual
  • ABC Caregiver Booklet
  • Anticholinergic Cognitive Burden Scale

LaMantia et al JAGS 2015; Frame et al eGEMS 2013; Monahan et al, JCIA 2010; Monahan et al JCIA 2012; Boustani et al, JCIA 2009

The ABC beta version Efficacy

  • NNT = 3.7
  • 7 NPI point improvement
  • Each 1 point decline in NPI = $250-$400 in health care expenses
  • Potential saving 1750-$2800 per patient
  • Improvement in family stress
Bar chart.
Callahan, Boustani et al, JAMA 2006

NNT: Number Need to Treat; NPI: Neuropsychiatric Inventory; CG: Caregiver

ABC 1.0 Performance

The Acute Care Service Utility Domain ABC PCC
% patients with at least one ER visit 28% 49%
Total number of ER visits 124 1143
% patients with at least one hospitalization 13% 26%
Total number of hospitalizations 45 438
Mean/Median length of hospital stay 5 / 4 7 / 4
ABC; Aging Brain Care patients; PCC: primary care center patients
Boustani et al, Aging & Mental Health 2011

 

The Quality of Care Indicator Domain ABC PCC
% seen at ER again within one week 14% 15%
% re-hospitalized within 30 days of discharge 11% 20%
% with at least one order of definite anticholinergics 19% 40%
% with at least one order of neuroleptics 5% 5%
% with at least one order of anti-dementia drugs 55% 13%
% with at least one order of antidepressant drugs 68% 48%
% with at least one order of definite anticholinergics and anti-dementia drugs 16% 32%
% with at least one LDL order 82% 72%
% of patients with LDL < 130 45% 23%
% with at least one HbA1c order 78% 62%
% of patients with HbA1c < 8 78% 51%
% with last systolic BP < 160 27% 24%
ABC; Aging Brain Care patients; PCC: primary care center patients
Boustani et al, Aging & Mental Health 2011

ABC 1.0 Annual Cost Savings Per Patient

Bar chart.
Total Cost Savings Per Patient Low Mid High
$2,885 $3,474 $4,227

ABC 2.0 Performance

Health Outcomes
Full Dementia Care Giver Responders at 12 months 66%
Full Major Depression Patients Responders at 12 months 51%
LaMantia et al, JAGS 2015

ABC DistributionPreferred Population Health Management, LLC

  • On-boarding of scalable and existing workforce within the AAAs. (multiple Mini Interview)
  • Training and ongoing management and support of the scalable workforce (combined experiential adult learning based coaching)
  • Ongoing Zoom-in & Zoom-out monitoring of the performance of the entire population to allow both complex case management and comprehensive resource allocation for the entire population at Risk (Population Health Logistic software)
  • Evidence-based clinical pathway to mange the complex cognitive, functional, behavioral and psychological needs of both the client (member suffering from the disease) and their family caregiver.